Equipe Dynamique du proton dans les compartiments cellulaires et intracellulaires
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[2020] Pyrazine Ring-Based Na +/H + Exchanger (NHE) Inhibitors Potently Inhibit Cancer Cell Growth in 3D Culture, Independent of NHE1. 2020. Apr 2;10(1):5800.
Michala G Rolver, Line O Elingaard-Larsen, Anne P Andersen, Laurent Counillon and Stine F Pedersen. 19-06-2020 -
[2019] The SLC9A-C Mammalian Na+/H+ Exchanger Family: Molecules, Mechanisms, and Physiology. Physiological Reviews. 2019; Oct 1;99(4):2015-2113.
S. F. Pedersen and L. Counillon 16-09-2019 -
[2017] CD95-Mediated Proton Regulation. Methods Mol Biol. 2017;1557:95-102.
Cophignon A, Poët M, Monet M, Tauc M, Counillon L. 08-08-2017 -
[2016] Na(+)/H(+) antiporter (NHE1) and lactate/H(+) symporters (MCTs) in pH homeostasis and cancer metabolism. Biochim Biophys Acta. 2016 Oct;1863(10):2465-80.
Counillon L, Bouret Y, Marchiq I, Pouysségur J. 08-08-2017 -
[2016] The cleaved FAS ligand activates the Na(+)/H(+) exchanger NHE1 through Akt/ROCK1 to stimulate cell motility. Sci Rep. 2016 Jun 15;6:28008.
Monet M, Poët M, Tauzin S, Fouqué A, Cophignon A, Lagadic-Gossmann D, Vacher P, Legembre P, Counillon L. 08-08-2017 -
[2015] Functional characterization of Na+/H+ exchangers of intracellular compartments using proton-killing selection to express them at the plasma membrane. J Vis Exp. 2015 Mar 30;(97).
Milosavljevic N, Poët M, Monet M, Birgy-Barelli E, Léna I, Counillon L. 08-08-2017 -
[2014] Capturing intracellular pH dynamics by coupling its molecular mechanisms within a fully tractable mathematical model. PLOS ONE 9(1) e8544
Bouret Y, Argentina M and Counillon L. 27-07-2015 -
[2014] The intracellular Na(+)/H(+) exchanger NHE7 effects a Na(+)-coupled, but not K(+)-coupled proton-loading mechanism in endocytosis. Cell Rep. 2014 May 8;7(3):689-96.
Milosavljevic N, Monet M, Léna I, Brau F, Lacas-Gervais S, Feliciangeli S, Counillon L, Poët M. 08-08-2017 -
[2013] NaV1.5 Na⁺ channels allosterically regulate the NHE-1 exchanger and promote the activity of breast cancer cell invadopodia. J Cell Sci. 2013 Nov 1;126(Pt 21):4835-42.
Brisson L, Driffort V, Benoist L, Poet M, Counillon L, Antelmi E, Rubino R, Besson P, Labbal F, Chevalier S, Reshkin SJ, Gore J, Roger S. 08-08-2017 -
[2013] Hypoxia promotes tumor cell survival in acidic conditions by preserving ATP levels. J Cell Physiol. 2013 Sep;228(9):1854-62.
Parks SK, Mazure NM, Counillon L, Pouysségur J. 08-08-2017 -
[2012] On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry. Cell Biochem Biophys. 2012 May;63(1):47-57.
Pang V, Counillon L, Lagadic-Gossmann D, Poet M, Lacroix J, Sergent O, Khan R, Rauch C. 08-08-2017 -
[2011] Teaching new dogs old tricks: membrane biophysical properties in drug delivery and resistance. Recent Pat Anticancer Drug Discov. 2011 Sep;6(3):334-46.
Milosavljevic N, Blanchard A, Wahl ML, Harguindey S, Poet M, Counillon L, Rauch C. 08-08-2017 -
[2010] The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway. PLoS Biol. 2011 Jun;9(6):e1001090.
Tauzin S, Chaigne-Delalande B, Selva E, Khadra N, Daburon S, Contin-Bordes C, Blanco P, Le Seyec J, Ducret T, Counillon L, Moreau JF, Hofman P, Vacher P, Legembre P. 08-08-2017 -
[2010] Nongenomic effects of cisplatin: acute inhibition of mechanosensitive transporters and channels without actin remodeling. Cancer Res. 2010 Oct 1;70(19):7514-22.
Milosavljevic N, Duranton C, Djerbi N, Puech PH, Gounon P, Lagadic-Gossmann D, Dimanche-Boitrel MT, Rauch C, Tauc M, Counillon L, Poët M. 08-08-2017