Presentation of the LP2M

The Laboratory of Molecular PhysioMedicine (LP2M) is a research unit organized around 2 major research axes: (i) pathophysiology of ion transport with application in the renal, cardiovascular, muscular and neurosensory systems and (ii) osteo-immunology (bone and immune cell interactions) in physiological condition and in chronic inflammatory diseases.

The LP2M was created in 2012 and is hosted by the Centre National de la Recherche Scientifique (CNRS) and the University Nice Sophia Antipolis (UNS) member of the Université côte d’azur (UCA). It brings together basic researchers, clinicians, technicians, engineers, and students at all stages of their curriculum, representing about 40 people.

With our complementary expertise, we develop multidisciplinary research programs, from molecules to patients, focused on the physiopathology of the bone, renal, vascular, immune, and neurosensory systems through two main aspects:  ion transport and osteo-immune interactions.

We study both the molecular mechanisms involved in the control cellular potential, pH or oxidative status, and the mechanisms of inflammation and the associated inflammatory bone destruction. Our projects have clinical applications and a strong transfer potential for chronic diseases (Neurological and cardiovascular disorders, Crohn's disease, arthritis), osteoporosis, ischemia, transplantation and cancer.

Our Laboratory is member of national and excellence initiatives such as the ICST Labex, and the UCA JEDI Idex and international consortia. It is also developing strong interaction with the socio-economic sector.

 

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