Lab presentation

The Laboratory of Molecular Physiomedicine (LP2M) is a research laboratory organized around 2 axis: (i) pathophysiology of ion transport with application in the renal, vascular, muscular and neurosensory systems and (ii) osteo-immunological interactions (between bone and immune cells) in physiological condition and in chronic inflammatory diseases.

The LP2M was created in 2012 under the governance of the Centre National de la Recherche Scientifique (CNRS) and the University Nice Sophia Antipolis (UNS), member of the Univesity Côte d'Azur (UCA). It brings together basic researchers, clinicians, technicians, engineers, and students at all stages of their cursus, representing about 40 people.

With these complementary competences, we develop multidisciplinary research programs focused on the physiopathology of the bone, renal, immune, vascular, and neurosensory systems through two main aspects:  ion transport and osteo-immune interactions.

We study the molecular mechanisms involved in the regulation of intracellular pH, membrane potential or oxidative stress, as well as the causes and effects of inflammation and the associated bone destruction. Our projects have clinical applications and strong translational potential for chronic diseases (cardiovascular and neurological disorders, Crohn's disease, arthritis), oetsoporosis, ischemia, transplantation and cancer.

Our Laboratory is participating in national and international initiatives including the ICST Labex, the UCA-JEDI Idex and international consortium. It is  developing basic, preclinical and clinical projects as well as  strong interaction with the socio-economic sector.

 

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