Offre de Post-Doc


We are seeking a highly motivated and talented post-doctoral researcher interested in developing/extending expertise in osteoimmunology to join the team "Osteoimmunology, niches and inflammation. We will pay special attention to candidates willing to develop their career in France.

Project: Osteoclasts are monocytic cells responsible for bone resorption and pathological bone destruction. We recently showed that, as other monocytic cells, they are an heterogeneous family of innate immune cells participating in mmunosuppressive or inflammatory responses.

The candidate will participate in the in-depth characterization of the heterogeneity of the different osteoclast populations, of their contribution to inflammatory responses and the conditions in which they differentiate. Considering this heterogeneity is a very novel picture in osteoclast biology. Our team is one of the very few teams expert in this field. Our aim is to better identify new clues for diagnosis and therapeutic strategies as well as novel information on osteoclast origin and immune function that have been neglected up to now.

Host laboratory: Our laboratory is depending on the CNRS, the main research body in France, and the Université Côte d'Azur labeled as "University of Excellence". Located in the Faculty of Medicine in the heart of Nice, it provides a high-quality scientific environment with access to all required core facilities as well as interaction with clinicians.

Requirements: We are seeking a highly motivated and talented post-doctoral researcher with a strong background in osteoimmunology or immunology, assessed by publications. Strong experience in cell biology, flow cytometry, RNAseq and computational analysis and animal experimentation is required. Ability to work independently, and excellent team communication and organization skills are essential. French or English practice is mandatory.

The position is funded for 1 year, with the possibility of renewal for 2 more years. The salary is 30 to 45 k€ annual gross depending on the experience. Moreover, if independent thinking and capacity to undertake responsibility as project leader are proven together with excellent track records, the postdoc will be supported to apply for a permanent position in the team.

To apply: Applicants should submit (in French or in English) their CV and publication list, the name and e-mail of 3 references and a brief statement of past achievements and research interests to Dr . Deadline for application: July 1st, 2020.

Starting: the position is available as soon as possible, and before the end of 2020.

A postdoc position is open in Team 1 for a period of 18 month starting if possible as early as September 2019.

Our laboratory, LP2M UMR7370 is recruiting an international post doctoral fellow for a period of 18 month starting if possible as early as September 2019.

The candidate will work on a transdisciplinary project aimed at deciphering the relations between the activities of Na+/H+ exchangers, Na+ Channels and Na/K ATPase in the field of cellular metabolic reprogrammation, motility and invasiveness. The experimental approaches will combine ion transport and cellular measurements with transcriptomics and metabolomics and will therefore involve the analysis of large sets of data.

The candidate will benefit from the infrastructures of LP2M and of the surrounding technical platforms: Electrophysiology, atomic absorption spectrometry analytical HPLC, flow cytometry, videomicroscopy, genomics, imaging, metabolomics... The candidate will also work in collaboration with colleagues from the Maths/Physics and computing departments for data analysis and model construction.

The candidate will have to possess a high-level expertise in ion transport, cellular biology and metabolism to perform the experimental parts of the project. An expertise in mathematical and or computational approaches of biology is not mandatory but will be appreciated.

 

Additional information:

Approximate net salary : 2400€/month

Please send a detailed CV and two names of scientific colleagues or former supervisors, for reference to

The Laboratory of Oceanography of Villefranche-sur-Mer, France in collaboration with LP2M (Team 1) Is recruiting a postdoc for 18-24 months. Expected date of employment : 1st October 2019 Deadline : 30th June 2019

Post-Doc fellowship in biological fractionation of non-traditional isotopes


General information

Workplace : Lab of Oceanography of Villefranche-sur-Mer, France (http://www.lov.obs-vlfr.fr/)
Date of publication : 20th May 2019
Type of Contract : FTC Scientist (full time)
Contract Period : between 18 to 24 months according to experience
Expected date of employment : 1st October 2019
Remuneration : between 2500 and 3500 euros gross monthly according to experience
Desired level of education : PhD
Experience required : Indifferent
Deadline for application: 30th June 2019


Missions

The relationships between the concentrations of trace metals and marine biomass and biodiversity remain uncertain. The ISO2MET ANR project targets to apply stable isotope fractionations of trace metals in marine ecotoxicology, and to determine the relationships between isotope signatures of marine species, marine carbonates and metal levels in the ocean.


Activities

The post-doc will focus his/her activity on characterizing and quantifying biological fractionation of lithium, copper and zinc isotopes in the marine environment. The post-doc will also participate to the experimental work initiated at the cellular level, in collaboration with a laboratory located at the Faculty of Medicine in Nice. At the organism level, the candidate will perform high sensitivity isotopic measurements on plankton, plankton-feeders, fishes, bivalves and corals, collected in contrasted environments, or cultured under controlled conditions. The objective is to establish the control laws of biological isotope fractionations in the ocean and to provide new approaches in ecotoxicology, paleoenvironment and medical fields.


Skills

Candidates should hold a PhD in non-traditional isotopes in the environment and have significant skills in biology and/or paleo-environments. Experience in modeling isotopic and geochemical data would be an asset. The capacity to work in a multidisciplinary team, and the ability to communicate and write easily in English is essential. Additional expertise will be appreciated in ecotoxicology and environmental science.

 

Work context

LOV is a joint research unit of both the CNRS and Sorbonne University, and is a French marine station specialized in plankton ecology, ocean acidification and marine biogeochemical cycles. At LOV, the post-doc will participate to the newly formed Chemistry-Ocean-Climate (CHOC) team dynamics, that involve 8 researchers, technical staffs and several PhD students. In the context of the project, the post-doc will be part of the ANR ISO2MET team and will benefit from the interdisciplinary and numerous interactions of its members from LOV, LP2M (Nice), IAEA-Monaco, LIENSs (LaRochelle) and ENS-Lyon (https://anr.fr/Project-ANR-18-CE34-0002). Equipped clean laboratories, ICP-OES, ICP-MS, GC and EA-IRMS are part of the CHOC and the LIENSs platforms. MC-ICP-MS are available in ENS-Lyon. Modeling is performed in collaboration with Nice University biophysicists.


Application

Send applications (CV, name of two referents, motivation letter) or questions to   and to before 30th June 2019.